Indena S.p.A
Since 1921, in a landscape of conservative nature lovers, we have been the progressive people looking at nature in another way, through science, constantly following the plants.
History moves as fast as Indena’s innovations: 100 years of ideas, inventions, products and patents that, in addition to leaving a permanent mark on the industry of nature, have been woven into the history of Italy.
Indena Phytosome®
Indena Phytosome® enhances the effectiveness and target reach of a wide range of ingredients, allowing them to give their best. This means Indena Phytosome® is able to:
Optimize the absorption rate and PK profile of selected ingredients
Improve their dissolution profile
Achieve physical and chemical stability
Optimize interaction with gut microbiome
Optimize efficacy and safety profile > no pharmacological adjuvants | no structural / chemical modification
Provide flexibility > suitable for several dosage forms
Be customized > tailor-made formulations
Be safe and well-tolerated over time > supported by numerous rigorous scientific studies
Be fully vegan-friendly
Centextra® (Centella asiatica Extract)
Centextra® is a standardized Centella asiatica extract developed using Indena's proprietary phytosome and botanical extraction expertise to preserve key triterpenes responsible for its biological activity. Clinical studies support its ability to promote connective tissue health, improve microcirculation, enhance wound healing, and support skin elasticity, making it ideal for beauty-from-within, vascular health, and healthy aging formulations.
Key Points (Advantages):
Advanced Skin Health
Supports collagen production, skin elasticity, and overall skin wellness.Enhanced Bioavailability
Combines Centella asiatica extract with Indena's Phytosome® technology for improved absorption and effectiveness.Science-Backed
Standardized in active triterpenes and supported by scientific research for skin health and repair.Premium Botanical Quality
Responsibly sourced and manufactured to ensure consistent quality, purity, and sustainability.
Anthocran® (Cranberry Extract)
Anthocran® is a premium Cranberry extract standardized for proanthocyanidins (PACs), the bioactive compounds responsible for supporting urinary tract health by reducing bacterial adhesion to the urinary tract lining. Backed by clinical research, Anthocran® also provides antioxidant protection and supports urinary wellness, making it suitable for women's health supplements, functional beverages, gummies, and capsules.
Key Points (Advantages):
Urinary Health Specialist
Supports urinary tract wellness by helping reduce bacterial adhesion.High-Quality Cranberry Extract
Standardized for cranberry proanthocyanidins (PACs), the key active compounds.Antioxidant Protection
Provides polyphenols that help protect cells from oxidative stress.Clinically Supported
Backed by human studies supporting urinary tract health benefits.
Siliphos® (Silybin)
Siliphos® is a patented Silybin Phytosome® that significantly enhances the bioavailability of milk thistle's most active compound, providing superior liver protection against oxidative stress and environmental toxins. Clinically supported to promote healthy liver function and cellular detoxification, Siliphos® is ideal for liver health, metabolic wellness, and healthy aging supplements.
Key Points (Advantages):
Enhanced Liver Support
Provides highly bioavailable silybin to support liver protection and function.Superior Absorption
Phytosome technology improves bioavailability compared with conventional silymarin.Antioxidant Defense
Helps protect liver cells against oxidative stress.Clinically Validated
Supported by human studies demonstrating improved absorption and effectiveness.
Silymarin (Silymarin Extract)
Silymarin is a standardized extract from milk thistle (Silybum marianum) containing a complex of flavonolignans that provide potent antioxidant and hepatoprotective properties. It has been extensively studied for supporting liver cell regeneration, protecting against oxidative stress, and promoting normal liver function, making it a foundational ingredient in liver health supplements.
Key Points (Advantages):
Traditional Liver Wellness ingredient
Derived from milk thistle, a well-established botanical for liver support.Antioxidant Protection
Helps defend liver cells against free radicals and oxidative damage.Healthy Liver Function
Supports normal liver metabolism and detoxification pathways.Quality Standardized Extract
Provides consistent flavonolignan content for reliable supplementation.
Cronilief® (Palmitoylethanolamide)
Cronilief® is a patented palmitoylethanolamide (PEA) Indena Phytosome® that supports the body's natural ability to manage chronic pain and inflammation through enhanced PEA absorption. Clinically shown to provide up to six times greater bioavailability than conventional PEA, Cronilief® helps relieve chronic discomfort and lower back pain, making it ideal for mobility and healthy aging formulations.
Key Points (Advantages):
Supports Joint & Muscle Comfort
Helps relieve everyday aches and supports long-term comfort.Enhanced Absorption
Uses Indena's Phytosome® technology to improve the absorption and effectiveness of PEA.Clinically Proven
Backed by human clinical studies demonstrating support for chronic pain management and physical comfort.Premium Quality
Developed with patented Phytosome® technology to ensure consistent quality, purity, and performance.
Quercefit® (Quercetin)
Quercefit® is a premium quercetin Phytosome® formulation developed by Indena using its advanced delivery technology to enhance the potential of quercetin in modern wellness applications. Backed by extensive clinical research, Quercefit® supports healthy aging, immune wellness, physical performance, and overall resilience, making it a versatile ingredient for longevity, active lifestyle, beauty-from-within, and wellness supplements.
Key Points (Advantages):
Superior Absorption
Utilizes Indena's patented Phytosome® technology to enhance quercetin absorption, delivering up to 20x greater bioavailability than standard quercetin.
Immune & Inflammatory Support
Helps support a healthy immune response and promotes a balanced inflammatory response for overall wellness.
Exercise Performance & Recovery
Supports physical performance, reduces exercise-related fatigue, and promotes faster recovery and muscle comfort after physical activity.
Clinically Studied
Backed by more than 10 human clinical studies demonstrating benefits for healthy aging, immune health, physical performance, fatigue reduction, eye health, and healthy inflammatory response.
Premium Botanical Quality
High-quality quercetin from Sophora japonica, manufactured by Indena with standardized quality, purity, and scientifically validated performance.
GinkgoSelect® (Ginkgo biloba Extract)
GinkgoSelect® is a premium standardized Ginkgo biloba extract manufactured using Indena's advanced botanical extraction technology to ensure consistent levels of active flavonoids and terpene lactones. Clinical evidence supports improvements in memory, cognitive performance, circulation, and healthy aging, making it widely used in brain health and cognitive wellness supplements.
Key Points (Advantages):
Brain & Cognitive Support
Helps support memory, focus, mental performance, and healthy cognitive function.Healthy Circulation
Promotes healthy blood circulation to support brain, eye, and overall vascular health.Clinically Studied
Backed by scientific research demonstrating its benefits for cognitive health and circulation.Premium Botanical Quality
Standardized Ginkgo biloba extract manufactured using Indena's expertise for consistent quality, purity, and performance.
Relissa® (Lemon Balm Extract)
Relissa® is a proprietary lemon balm (Melissa officinalis) extract standardized for key bioactive compounds that promote relaxation without causing drowsiness. Clinical studies have shown that Relissa® helps reduce stress, improve mood, support sleep quality, and enhance mental well-being, making it suitable for stress management and emotional wellness formulations.
Key Points (Advantages):
Stress & Sleep Support
Helps promote relaxation, reduce stress, and improve sleep quality.Clinically Proven
A clinical study showed significant improvements in sleep quality, stress levels, and overall well-being after 3 weeks of supplementation.Enhanced Bioavailability
Combines lemon balm extract with Indena's Phytosome® technology for improved absorption and effectiveness.Premium Botanical Quality
Made from standardized Melissa officinalis (lemon balm) extract to ensure consistent quality and performance.
Berbevis® (Berberine Extract)
Berbevis® is a highly bioavailable phytosome formulation of berberine designed to overcome the poor absorption associated with conventional berberine extracts. Clinical research supports its role in maintaining healthy blood glucose metabolism, improving insulin sensitivity, supporting cardiovascular health, and promoting metabolic wellness.
Key Points (Advantages):
Metabolic Health Support
Helps support healthy blood sugar, cholesterol, and overall metabolic wellness.Enhanced Bioavailability
Uses Indena's Phytosome® technology to improve the absorption and effectiveness of berberine.Clinically Proven
A 60-day clinical study showed improvements in blood sugar, insulin sensitivity, and metabolic health.Premium Botanical Quality
Made from standardized berberine with Indena's patented delivery technology for consistent quality, purity, and performance.
Greenselect® (Green Tea Extract)
Greenselect® is a caffeine-free, highly standardized green tea extract to enhance the bioavailability of EGCG and tea catechins, helping promote antioxidant protection, thermogenesis, and a healthy metabolism. Clinically shown to support body weight management, lipid metabolism, and metabolic balance when combined with a healthy lifestyle, Greenselect® is an ideal ingredient for weight management, metabolic wellness, and women's health formulations.
Key Points (Advantages):
Weight Management Support
Helps support healthy weight management by promoting fat metabolism and energy expenditure.Enhanced Bioavailability
Uses Indena's Phytosome® technology to improve the absorption of green tea catechins.Clinically Proven
Clinical studies demonstrated significant reductions in body weight, waist circumference, and body fat when combined with a healthy lifestyle.Premium Botanical Quality
Made from decaffeinated, standardized green tea for consistent quality and performance.
CUBO® (Curcumin + Bowellia)
CUBO® is a patented combination of Curcuma longa and Boswellia serrata Indena Phytosome® extracts that supports gut health by helping reduce abdominal bloating, discomfort, and intestinal dysbiosis through improved bioavailability and complementary botanical actions. Clinically shown to significantly improve bloating intensity, abdominal pressure, and microbiota balance within 30 days, CUBO® is an innovative ingredient for digestive wellness and gastrointestinal health formulations.
Key Points (Advantages):
Common Digestive Concern
20-30% of the general population suffers from functional gastrointestinal discomfort.Enhanced Absorption
Features Indena's Phytosome® technology to improve the bioavailability and absorption of curcumin and boswellia compared to conventional extracts.Premium Botanical Quality
Combines Curcumin Indena Phytosome® and Boswellia Indena Phytosome®, two clinically studied botanical ingredients that work together to support digestive comfort.Clinically Proven
A clinical study demonstrated reduced bloating and improved digestive comfort in just 30 days
Casperome® (Boswellia Extract)
Casperome® is a proprietary Boswellia (Boswellia serrata) extract formulated with Indena's Phytosome® technology to enhance the absorption of boswellic acids and support a healthy inflammatory response. Clinically studied for its benefits in joint, musculoskeletal, respiratory, and gut health, it helps promote mobility, digestive comfort, and overall physical well-being.
Key Points (Advantages):
Joint Comfort & Mobility
Helps support joint comfort, flexibility, and healthy mobility.Enhanced Absorption
Uses Indena's Phytosome® technology to improve boswellia absorption.Clinically Proven
Clinical studies showed improvements in joint comfort and mobility within 5 days.Premium Extract
Made from standardized Boswellia serrata for consistent quality and performance.
Leucoselect® (Grapeseed Extract)
Leucoselect® is a standardized grape seed (Vitis vinifera) extract rich in oligomeric proanthocyanidins (OPCs), known for its powerful antioxidant properties that help protect cells from oxidative stress. It supports cardiovascular health, healthy circulation, and overall wellness, while also promoting healthy aging and skin vitality.
Key Points (Advantages):
Premium Grape Seed Extract
Made from standardized grape seed extract, naturally rich in polyphenols.Enhanced Absorption
Uses Indena's Phytosome® technology for improved absorption.Clinically Proven
Clinical studies showed support for vascular health and antioxidant protection.Trusted Quality
Developed with Indena's patented technology for consistent quality and performance.
Meriva® (Turmeric Extract)
Meriva® supports a healthy inflammatory response to promote joint comfort, mobility, muscle recovery, and overall healthy aging. Its patented Phytosome® technology significantly enhances curcumin absorption, enabling greater bioavailability and clinical efficacy than conventional curcumin extracts.
Key Points (Advantages):
Joint & Mobility Support
Helps support joint comfort, flexibility, and healthy mobility.Enhanced Absorption
Uses Indena's Phytosome® technology to improve the absorption of curcumin.Clinically Proven
Clinical studies showed improvements in joint comfort, physical function, and mobility.Premium Curcumin Extract
Made from standardized curcumin with Indena's patented Phytosome® technology for consistent quality and performance.
Vazguard® (Bergamot Extract)
Vazguard® is formulated with Indena's Phytosome® technology to enhance the bioavailability of bergamot polyphenols, supporting healthy cholesterol levels, blood sugar balance, liver function, and cardiovascular wellness. Its versatility makes it suitable for metabolic health supplements, heart health formulations, healthy aging products, and functional foods and beverages targeting overall cardiometabolic wellness.
Key Points (Advantages):
Metabolic Health Support
Helps support healthy blood sugar, cholesterol, liver health, and overall metabolic balance.Enhanced Absorption
Uses Indena's Phytosome® technology to improve the absorption of bergamot polyphenols.Clinically Proven
A clinical study showed a 12% reduction in visceral fat along with improvements in blood sugar and cholesterol levels.Premium Bergamot Extract
Made from standardized bergamot extract for consistent quality and performance.
Ubiqsome® (Coenzyme Q10)
Ubiqsome® is an advanced CoQ10 ingredient formulated with Indena's Phytosome® technology to enhance bioavailability and deliver CoQ10 directly to muscles, cells, and mitochondria, where it supports cellular energy production. Clinically shown to improve physical performance, cardiovascular function, muscle health, skin health, and healthy aging, it is well suited for sports nutrition, energy, heart health, beauty-from-within, and healthy aging formulations.
Key Points (Advantages):
Cellular Energy Support
Helps support energy production, heart health, and overall vitality.Enhanced Absorption
Uses Indena's Phytosome® technology to improve the absorption of Coenzyme Q10 (CoQ10).Clinically Proven
Clinical studies showed significantly higher CoQ10 bioavailability compared to conventional CoQ10 formulations.Premium CoQ10 Quality
Made with high-quality CoQ10 and Indena's patented Phytosome® technology for consistent quality and performance
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